src oncogenes การใช้

His work on mutants of the Rous sarcoma virus enabled Michael Bishop and Harold Varmus to isolate DNA sequences that represent the src oncogene and to demonstrate the cellular origin of oncogenes.
The C-gamma-1 and C-gamma-2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3 . [ supplied by OMIM]
Their best-known accomplishment was the identification of a cellular gene ( c-src ) that gave rise to the v-src oncogene of Rous Sarcoma Virus, a cancer-causing virus first isolated from a chicken sarcoma by Peyton Rous in 1910.
An example of an acute transforming virus is the Rous Sarcoma Virus ( RSV ) that carry the v-src oncogene . v-Src is part of the c-src, which is a cellular proto-oncogene that stimulates rapid cell growth and expansion.